MK-677
Orally active ghrelin mimetic and GH secretagogue
Ibutamoren Mesylate (MK-677)
MK-677 (Ibutamoren) is an orally active, non-peptide ghrelin receptor agonist and growth hormone secretagogue. By mimicking the action of ghrelin at the GHS-R1a receptor, it stimulates pulsatile growth hormone release and elevates IGF-1 without suppressing endogenous production. Its long half-life and oral bioavailability make it a widely used reference compound in studies of the GH/IGF-1 axis, appetite signaling, sleep architecture, and body composition.
For Research Use Only
Not for human consumption, veterinary use, or any therapeutic applications. Purchase requires valid research credentials.
Purity
Purity Exceeds 99%
Storage
2–8°C
Form
Lyophilized
Grade
Research
MK-677 Overview
MK-677 (Ibutamoren) is an orally active, non-peptide ghrelin receptor agonist and growth hormone secretagogue. By mimicking the action of ghrelin at the GHS-R1a receptor, it stimulates pulsatile growth hormone release and elevates IGF-1 without suppressing endogenous production. Its long half-life and oral bioavailability make it a widely used reference compound in studies of the GH/IGF-1 axis, appetite signaling, sleep architecture, and body composition.
Specifications
| Composition | Ibutamoren Mesylate (MK-677) |
|---|---|
| Molecular Formula | C27H36N4O5S |
| Half-Life | ~24 hours |
| Purity | Purity Exceeds 99% |
| Available Sizes | 25mg |
| Storage | 2–8°C, protect from light |
| SKU | MK25 |
| Grade | Research / Laboratory use only |



